a tool for identifying drug-targetable redox-active disulphides

Beta-lactoglobulin-1

Intramolecular

Cysteine 124 and cysteine 137

A redox-regulated disulphide may form within Beta-lactoglobulin-1 between cysteines 124 and 137 (106 and 119 respectively in this structure).

Details

Redox score ?

78

PDB code

Structure name

crystal structure of gyuba, a patched chimera of b-lactglobulin

Structure deposition date

2009-12-08

Thiol separation (Å)

2

Half-sphere exposure sum ?

94

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

124

Residue number B

137

Peptide name

Beta-lactoglobulin-1

Ligandability

Cysteine 124 of Beta-lactoglobulin-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 137 of Beta-lactoglobulin-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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